This article is structured in two parts. In the first part there is a focus on Deleuze’s philosophy and in particular the question of desert(ed) islands. Running throughout this section is a consistent concern with empathy and sociality, with the changing structure of alterity in the identified movement from neurosis, psychosis to perversion. In this section I make the argument that several forms of contemporary philosophy are carrying out acts of philosophical autism with regards to species extinction and the question of the absence of the other. I try to counter this trend in the second part of the paper where there is a concern with thinking the structure “Us-without-world,” which is my original contribution. In the time of the coronavirus pandemic, in the time of our forced solitude, in the time of our intoxication with technology, there is a real problem of the life-world, of thinking we-experience in common life, in this new hermetic reality. This is encapsulated in the thought-experiment of the structure “Us-without-world”.